VapoMeter - Reference publications

Transepidermal water loss TEWL, Skin barrier function, Penetration studies

Skin irritation

Effect of skin care, treatment, nutrition

Scalp, lip and nail measurements

Wound healing

Skin surface water loss SSWL

Physiological and Sympathetic skin response, Hyperhidrosis

Veterinary dermatology and skin behaviour, treatment and nutrition, Zoology

In-vitro studies

Validation articles

Transepidermal water loss TEWL, Skin barrier function, Penetration studies

Epidermal ceramidase activity regulates epidermal desquamation via stratum corneum acidification
Houben E., Hachem J.P., de Paepe K. and Rogiers V.
Skin Pharmacol Physiol, 21:111-118, 2008.

Increased carbonyl protein levels in the stratum corneum of the face during winter
Kobayashi Y., Iwai I., Akutsu N. and Hirao T.
Int J Cosmet Sci, 30, 35-40, 2008.

Cytokines at different stratum corneum levels in normal and sodium lauryl sulphate-irritated skin
de Jongh C.M., Verberk M.M., Spiekstra S.W., Gibbs S. and Kezic S.
Skin Res Technol, Vol 13: 390-398, 2007.

Skin barrier structure and function and their relationship to puritus in end-stage renal disease
Yosipovitch G., Duque M.I., Pate T.S., Ishiuji Y., Guzman-Sanchez A., Dawn A.G., Freedman B.I., Chan Y.H., Crumrine D. and Elias P.M.
Nephrol Dial Transplant, Nov;22(11):3268-72, 2007.

Potential mechanisms by which a single drink of alcohol can increase transdermal absorption of topically applied chemicals
Brand R.M., Jendrzejewski J.L. and Charron A.R.
Toxicology, Jun 25;235(3): 141-149, 2007.

Increased permeability for polyethylene glycols through skin compromised by sodium lauryl sulphate
Jakasa I., Verberk M.M., Bunge A.L., Kruse J. and Kezic S.
Exp Dermatol, Oct;15(10): 801-7, 2006.

Altered penetration of polyethylene glycols into uninvolved skin of atopic dermatitis patienst
Jakasa I., Verberk M.M., Esposito M., Bos J.D. and Kezic S.
J Invest Dermatol, 127: 129-134, 2006.

'Keratolytic' properties of benzoyl peroxide and retinoic acid resemble salicylic acid in man
Waller J.M., Dreher F., Benham S., Ford C., Lee C., Tiet T., Weinstein G.D. and Maibach H.I.
Skin Pharmacol Physiol, Vol 19(5): 283-289, 2006.

Percutaneous penetration of sodium lauryl sulphate is increased in uninvolved skin of patients with atopic dermatitis compared with control subjects
Jakasa I., de Jongh C.M., Verberk M.M., Bos J.D. and Kezic S.
Br J Dermatol, Jul;155(1): 104-9 2006.

Variation in barrier impairment and inflammation of human skin as determined by sodium lauryl sulphate penetration rate
De Jongh C.M., Jakasa I., Verberk M.M. and Kezic S.
Br J Dermatol, Apr;154(4): 651-7, 2006.

Transepidermal water loss reflects permeability barrier status: validation in human and rodent in vivo and ex vivo models
Fluhr J.W., Feingold K.R. and Elias P.M.
Exp Dermatol, Jul;15(7): 483-92, 2006.

Determination of polyethylene glycols of different molecular weight in the stratum corneum
Jakasa I., Calkoen F. and Kezic S.
J Chromatogr B Analyt Technol Biomed Life Sci, Nov 25;811(2): 177-182, 2004.

Abstracts

Teprenone (Geranylgeranylacetone=GGA), a novel isoprene analog of geranylgeranylphosphate prolongs cell survival and improves skin condition
Lintner K., Mas Chamberlin C., Mondon P and Benech P.
Presentation at IFSCC 2007 in Amsterdam, 24-26 Sep 2007.

Variability in the physical properties of the stratum corneum – influences of chronological age and season: 001
Agarwal V., Godfrey M., Long S., Whitby D., Barton S. and Desnos A.
Int J Cosmet Sci, 29(3):219, June 2007.

Mechanism of injury and countermeasures for EVA associated upper extremity medical issues: Extended Vent Tube Study
Jones J., Hoffman R., Harvey G., Bowen C.K., Hudy C.E., Tuxhorn J., Gernhardt M. and Scheuring R.
Presentation at 15th International Academy of Astronautics’ “Humans in space” symposium in Beijing, 20-24 May 2007.

Assessing the gentleness of a sonic skin care brush for daily use
Henes E.M., Jackson L., Rodriguez S., Ortblad K. and Akridge R.
J Am Acad Dermatol 2006, 54(3):AB50 Poster 403

Assessment of permeability barrier function measuring transepidermal water loss: comparing 3 closed-loop systems and 4 open-loop systems in vivo and in vitro
Fluhr, J. W., Bankova, L., Elias, P. M. and Feingold, K. R.
Skin Res Technol, Vol 9 (2): 164, 2003.

Skin irritation

Skin Barrier Disruption by Sodium Lauryl Sulfate-Exposure Alters the Expressions of Involucrin, Transglutaminase 1, Profilaggrin, and Kallikreins during the Repair Phase in Human Skin In Vivo.
Törmä H., Lindberg M. and Berne B.
J Invest Dermatol, epub 15 Nov 2007.

Differential cytokine expression in skin after single and repeated irritation by sodium lauryl sulphate
de Jongh C.M., Lutter R., Verberk M.M. and Kezic S.
Exp Dermatol, 16, 1032-1040, 2007.

A randomized, controlled, double-blind study of the effect of wearing coated pH 5.5 latex gloves compared with standard powder-free latex gloves on skin pH, transepidermal water loss and skin irritation.
Mirza R., Maani N., Liu C., Kim J. and Rehmus W.
Contact Dermatitis, Jul;55(1): 20-5, 2006.

Stratum corneum cytokines and skin irritation response to sodium lauryl sulfate
de Jongh C.M., Verberk M.M., Withagen C.E.T., Jacobs J.J.L., Rustemeyer T. and Kezic S.
Contact Dermatitis, Jun;54(6):325-33, 2006.

Skin reaction and recovery: a repeated sodium lauryl sulphate patch test vs. a 24-h patch test and tape stripping
Koopman D.G., Kezic S., Verberk M.M.
Br J Dermatol, Mar;150(3):493-9, 2004.

Effect of skin care, treatment, nutrition

Evaluation of the antioxidant capacity and preventive effects of a topical emulsion and its vehicle control on the skin response to UV exposure
Zhai H., Behnam S., Villarama C.D., Arens-Corell M., Choi M.J. and Maibach H.I.
Skin Pharmacol Physiol, 18: 288-293, 2005.

Efficacy of dietary hempseed oil in patients with atopic dermatitis
Callaway J., Schwab U., Harvima I., Halonen P., Mykkänen O., Hyvönen P. and Järvinen T.
Dermatology Treat, 16: 87-94, 2005.

Moisturizing effects of topical nicotinamide on atopic dry skin
Soma Y., Kashima M., Imaizumi A., Takahama H., Kawakami T. and Mizoguchi M.
Int J Dermatol, Mar;44(3): 197-202, 2005.

Abstracts

Topical coconut oil application reduces trans-epidermal water loss (TEWL) in preterm very low birth weight neonates: A randomised clinical trial
Nangia S., Paul V.K. and Deorari A.K.
48th annual meeting of ESPR in Prague, Check Republic, 6 –8 Oct 2007, p. 105.
Pediatrics, Vol 121 Suppl 2, Jan 2008.

A pilot study of the efficacy and safety of pimecrolimus 1% cream in the treatment of Netherton syndrome: Interim results
Yan A., Shah K., Kubrak C. and Parneix-Spake A.
J Am Acad Dermatol, February: AB153, 2007.

Susceptibility to SLS irritation: Effect of a five-day pre-use of two skin care oils studied comparing various techniques and instruments
Rantanen, T., Snellman, E. and Kostiainen M.
First World Congress on Work-Related and Environmental Allergy, 9-12 July 2003: p. 95.

Scalp, lip and nail measurements

Influence of age and hormone replacement therapy on the functional properties of the lips
Caisey L., Gubanova E., Camus C., Lapatina N., Smetnik V. and Lévêque J.-L.
Skin Res Technol 2007 (epub on-line)

Water loss through lip, nail, eyelid skin, scalp skin and axillar skin measured with a closed-chamber evaporation principle
Nuutinen J., Harvima I., Lahtinen M.-R. and Lahtinen T.
Br J Dermatol, 148: 839-841, 2003.

Abstracts

Shampooing with pyrithione zinc reduces transepidermal water loss in scalp of dandruff-involved patients
Billhimer W., Erb J., Bacon R., Ertel K and Copas M.
J Am Acad Dermatol 2006, 54(3):Poster

Comparison of two instruments to assess scalp barrier function
Bacon R., Billhimer W., Ertel K. and Watson D.
Skin Res Technol, Vol 10: 13, 2004.

Wound healing

Abstracts

Evaluation of maceration by trans epidermal water loss (TEWL) in patients with venous leg ulcers
Dini V., Salibra F., Brilli C., Bertone M. and Romanelli M.
Sumposium on Advanced Wound Care & Medical Reseach Forum on Wound Repair, p. 128, 2006.

Skin surface water loss SSWL

Abstracts

Measurement of skin hydration in the diapered area of infants with a closed chamber TEWL meter
Alanen, E., Wiesemann, F., Nuutinen, J. and Lahtinen, T.
Skin Res Technol, Vol 9 (2): 199, 2003.

Physiological and Sympathetic skin response, Hyperhidrosis

Upper limb musculoskeletal disorders - With special reference to sympathetic nerve functions and tactile sensation
Ming Z.
Kuopio University Publications D. Medical Sciences 405. 2007. 91 p. MD Thesis.

Retroperitoneoscopic lumbar sympathectomy for the treatment of plantar hyperhidrosis: technique and preliminary findings
Rieger R. and Pedevilla S.
Surg Endosc, Jan;21(1):129-35, 2007.

Physiological and subjective responses to low relative humidity in young and elderly men
Sunwoo Y., Chou C., Takeshita J., Murakami M. and Tochihara Y.
J Physiol Anthropol, 25:229-238, 2006.

Physiological and subjective responses to low relative humidity
Sunwoo Y., Chou C., Takeshita J., Murakami M. and Tochihara Y.
J Physiol Anthropol, 25:7-14, 2006.

Abstracts

Objective evaluation of thoracoscopic sympathectomy for palmar hyperhidrosis
Tetteh H.A., Kast T., Maddaus M.M., Whitson B.A., Groth S.S., Radosevich D.M. and Andrade R.S.
44th Annual Meeting, The Society of Thoracic Surgeons, Jan 28-30, 2008, p. 176

Measurement of the amount of average hydrosis for giving data for scientific comparison
Pedevilla S. and Rieger R.
Presented in 7th International Symposium on Sympathetic Surgery, 20–22 March 2007
Clinical Autonomic Research, Vol 17, Number 2 / April 2007.

Veterinary dermatology and skin behaviour, treatment and nutrition, Zoology

Olopatadine ameliorates rat experimental cutaneous inflammation by improving skin barrier function
Tamura T., Matsubara M., Amano T. and Chida M.
Pharmacology; 81:118-126, 2008.

Potential mechanisms by which a single drink of alcohol can increase transdermal absorption of topically applied chemicals
Brand R.M., Jendrzejewski J.L. and Charron A.R.
Toxicology, Jun 25;235(3): 141-149, 2007.

Olopatadine hydrochloride accelerates the recovery of skin barrier function in mice
Amano T., Takeda T., Yano H. and Tamura T.
Br J Dermatol, May;156(5):906-912, 2007.

Cutaneous water loss and lipids of the stratum corneum in dusky anticirds, a lowland tropical bird
Munos-Garcia A. and Williams J.B.
The Condor, 109:59-66, 2007.

Transepidermal water loss reflects permeability barrier status: validation in human and rodent in vivo and ex vivo models
Fluhr J.W., Feingold K.R. and Elias P.M.
Exp Dermatol, Jul;15(7): 483-92, 2006.

Abstracts

Sweating rate of dairy cows under shade and sunny environments
Gebremedhin K.G., Hillman P.E., Lee C.N. and Collier R.J.
Presented at American Society of Agricultural and Biological Engineers Annual Meeting, 2007.

Regional differences in sweat rate response of steers to short-term heat stress
Spiers D.E., Wax L.E., Scharf B. and Aiken G.E.
J Anim Sci, Vol 84, Suppl 1/J Dairy Sci, Vol 89, Suppl 1: 303-304, 2006.

Effects of ambient temperature and solar radiation on skin evaporative water loss in dairy cattle
Pollar B.C., Dwyer, M.E., Fitzgerald A.C., Gentry P.C., Henderson D.A. and Collier R.J.
J Anim Sci, Vol 82, Suppl 1/J Dairy Sci, Vol 87, Suppl 1/Poult Sci Vol 83, Suppl 1: 198, 2006.

Impact of alcohol consumption on the skin as determined by non-invasive bioengineering tools
Brand R.M., Jendrzejewski J.L. and Charron A.R.
Society of Toxicology Meeting, March 2006.

Effects of ambient temperature and solar radiation on skin evaporative water loss in dairy cattle
Pollard, B. C., Dwyer, M. E., Fitzgerald, A. C., Gentry, P. C., Henderson, D. A. and Collier, R. J.
J Anim Sci, Vol 82, Suppl. 1/ J Dairy Sci, Vol 87, Suppl. 1/ Poult Sci, Vol 83, Suppl. 1. 198, 2004.

Heat dissipation in winter-acclimated lactating cows and non-lactating heifers subjected to increased ambient temperature and solar radiation in Arizona
Pollard, B. C., Annen, E. A., Baumgard, L. H., Cheatham, R. C., Estheimer, M. D., Dwyer, M. E., Fitzgerald, A. C., Halfliger, H. C., Moore, C. E., Kay, J. K., Mendivil, O. B., Gentry, P. C., Henderson, D. A., Steining, C. M. and Collier, R. J.
J Anim Sci, Vol 82, Suppl. 1/ J Dairy Sci, Vol 87, Suppl. 1/ Poult Sci, Vol 83, Suppl. 1. 461, 2004.

In-vitro studies

Qualitative and quantitative comparison of heat separated epidermis and dermatomed skin in percutaneous absorption studies
Atrux-Tallau N., Pirot F., Falson F., Roberts M.S. and Maibach H.I.
Arch Dermatol Res, Sep 28, 2007 (epub).

In vitro human skin model to evaluate water permeability and determine wound dressings' occlusivity
Zhai X., Yokota M. and Maibach H.I.
Cutan Ocul Toxicol ;26(2):107-11, 2007.

Vitamin C enhances differentation of a continuous keratinocyte cell line (REK) into epidermis with normal stratum cornuem ultrasructure and functional permeability barrier
Pasonen-Seppänen S., Suhonen T.M.,Kirjavainen M., Suihko E.,Urtti A., Miettinen M., Hyttinen M., Tammi M. and Tammi R.
Histocem Cell Biol, 116: 287-297, 2001.

Formation of permeability barrier in epidermal organotypic culture for studies on drug transport
Pasonen-Seppänen S., Suhonen T.M.,Kirjavainen M., Miettinen M., Urtti A., Tammi M. and Tammi R.
J Invest Dermatol, Vol 117, No 5, 1322-1324, November 2001.

Validation articles

Tape-stripping method in man: comparison of evaporimetric methods
Zhai H., Dika E., Goldovsky M. and Maibach H.I.
Skin Res Technol, Vol 13: 207-210, 2007.

Measurement of transepidermal water loss by closed-chamber systems
Nuutinen J.
in Serup J., Jemec G.B.E. and Grove G., (eds.), Handbook of non-invasive methods and the skin, 2nd edition, CRC Press, Boca Raton, FL, pp. 393-396, 2006.

Comparative evaporimetry in man
Shah J.H., Zhai H. and Maibach H.I.
Skin Res Technol, Vol 11: 205-208, 2005.

Validation of the VapoMeter, a closed unventilated chamber system to assess transepidermal water loss vs. the open chamber Tewameter
De Paepe K., Houben E., Adam R., Wiesemann F. and Rogiers V.
Skin Res Technol, Vol 11: 61-69, 2005.

Water loss through lip, nail, eyelid skin, scalp skin and axillar skin measured with a closed-chamber evaporation principle
Nuutinen J., Harvima I., Lahtinen M.-R. and Lahtinen T.
Br J Dermatol, 148: 839-841, 2003.

A closed unventilated chamber for the measurement of transepidermal water loss
Nuutinen J., Alanen E., Autio P., Lahtinen M-R., Harvima I. and Lahtinen T.
Skin Res Technol, Vol 9: 85-89, 2003.

Abstracts

Applicability of the closed unventilated VapoMeter to assess transepidermal water loss (TEWL) on nasolabial skin areas
De Paepe, K., Houben, E., Adam, R., Wiesemann, F. and Rogiers, V.
Skin Res Technol, Vol 10: 3, 2004.

Comparison of two methods for TEWL measurement
Shah J.H., Zhai H., Maibach H.I. and Nuutinen J.
Skin Res Technol, Vol 10, 2004.

Measurement of water evaporation rates with a closed chamber TEWL meter
Nuutinen, J., Alanen, E. and Lahtinen, T.
Skin Res Technol, Vol 9 (2): 183, 2003.